Thank you for your question! Histamine is typically released as a part of the inflammatory cascade. The mechanism of action of Atrantil reduces and eventually eliminates methane production, specifically in the small bowel. One of the direct results of high concentrations of methane is that the body can yield an inflammatory response. Atrantil is safe for the histamine hypersensitive consumer. Furthermore, Atrantil's formulation is considered a macromolecule, meaning there is little to no systemic uptake, resulting in no detectable interactions and no triggers for inflammation directly related to Atrantil consumption. We hope this helps to answer your question. Please let us know if we can be of further assistance.
Thank you and best wishes,
Support Team