Thank you for contacting us! It sounds like you have a very recalcitrant case of SIBO. We do have a few people who do not respond to the standard dosing over the 10 to 20 day period and some of those ended up feeling better after either going up on the dose (3 capsules 3 x's day) or staying on it longer (30-40 days). That being said, this is a moving target and ultimately we just want you to get better. Dr. Brown has treated some patients with a combination of Xifaxan or neomycin while taking Atrantil. Dr. Pimentel now recommends his patients to eat a high carb diet to see if the bacteria "soak up" the Xifaxan more, so that may be something to discuss with your doctor.
Since we have over an 80% success with SIBO patients taking Atrantil, you would want to make sure you are not missing anything else if it is not working. We would suggest speaking with your doctor and make sure nothing else is going on.
At the least we would recommend staying on Atrantil and take two capsules a day for the overall GI health benefit that the antioxidants and polyphenols provide. Hope this helps and sorry you are going through this tough time. Please let us know if we can be of further assistance.
Thank you and best wishes,
Support Team